KMID : 0371019960290010103
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Journal of Preventive Medicine and Public Health 1996 Volume.29 No. 1 p.103 ~ p.112
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Bronchial Hyperresponsiveness in Workers Exposed to Isocyanates
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Choi Kyeong-Sook
Kim Kyoo-Sang Choi Byung-Soon Choi Jung-Keun Lee Se-Wi Moon Young-Hahn
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Abstract
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We studied the association of nonspecific bronchial hyperresponsiveness with general characteristics, exposure concentration, respiratory symptoms, chest x-ray¢¥s! findings, past histories and pulmonary function. We determined bronchial hyperresponsiveness by methacholine challenge test. And we conducted a respiratory symptom questionnaire and performed spirometry on 111 workers occupationally exposed to isocyanates in various industries.
About 21.6% of subjects had bronchial hyperresponsiveness. No significant differences were observed between the hyperresponsive and non-responsive group with¢¥¢¥, I respect to age, sex, employment period, height, and smoking histories. Cough and breathlessness were significantly associated with the bronchial hyperresponsiveness. The hyperresponsive group had more experience of bronchitis and asthma in the past than the non-responsive group. The lower FEV, and FEV,% were closely related with bronchial hyperresponsiveness.
Bronchial hyperresponsiveness seems to be associated with some of respiratory symptoms, past histories and pulmonary function parameters in workers exposed to isocyanates.
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KEYWORD
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isocyanates, TDI, methacholine challenge test, bronchial hyperresponsiveness
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